Molecular Diagnostics of Cancer

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Molecular Diagnostics of Cancer Description

Present and potential future applications of new diagnostic strategies based on the direct or indirect detection of cancer genes are delineated in this volume. Among the methodological aspects covered are enzymatic target amplification by the polymerase chain reaction and related techniques, DNA fingerprinting, transfer of putative cancer genes in appropriate recipient cells, and recent developments in the application of monoclonal antibodies in immunohistochemistry and immunoscintigraphy. The diagnostic and functional implications of mutations in cancer genes such as ras and p53 are also described.

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